TitleDateAuthorsDOI
Genomics reveals introgression and purging of deleterious mutations in the Arabian leopard (Panthera pardus nimr)2023-09-15Mochales-Riaño, G; Fontsere, C; Manuel, MD; Talavera, A; Burriel-Carranza, B; Tejero-Cicuéndez, H; Algethami, RHM; Shobrak, M; Marques-Bonet, T; Carra (2023). Genomics reveals introgression and purging of deleterious mutations in the Arabian leopard (Panthera pardus nimr). Iscience, 26(9), 107481-. DOI: 10.1016/j.isci.2023.107481https://doi.org/10.1016/j.isci.2023.107481
Mutations on a conserved distal enhancer in the porcine C-reactive protein gene impair its expression in liver2023-09-14Hernández-Banqué, C; Jové-Juncà, T; Crespo-Piazuelo, D; González-Rodríguez, O; Ramayo-Caldas, Y; Esteve-Codina, A; Mercat, MJ; Bink, MCAM; Quintanilla (2023). Mutations on a conserved distal enhancer in the porcine C-reactive protein gene impair its expression in liver. Frontiers In Immunology, 14(), 1250942-. DOI: 10.3389/fimmu.2023.1250942https://doi.org/10.3389/fimmu.2023.1250942
Polystyrene nanoplastics target lysosomes interfering with lipid metabolism through the PPAR system and affecting macrophage functionalization2023-09-14Brandts, I; Sola, R; Garcia-Ordonez, M; Gella, A; Quintana, A; Martin, B; Esteve-Codina, A; Teles, M; Roher, N (2023). Polystyrene nanoplastics target lysosomes interfering with lipid metabolism through the PPAR system and affecting macrophage functionalization. Environmental Science-Nano, 10(9), 2245-2258. DOI: 10.1039/d2en01077ahttps://doi.org/10.1039/d2en01077a
ClinPrior: an algorithm for diagnosis and novel gene discovery by network-based prioritization2023-09-07Schlüter, A; Vélez-Santamaría, V; Verdura, E; Rodríguez-Palmero, A; Ruiz, M; Fourcade, S; Planas-Serra, L; Launay, N; Guilera, C; Martínez, JJ; Homede (2023). ClinPrior: an algorithm for diagnosis and novel gene discovery by network-based prioritization. Genome Medicine, 15(1), 68-. DOI: 10.1186/s13073-023-01214-2https://doi.org/10.1186/s13073-023-01214-2
Ghost admixture in eastern gorillas2023-09-01Pawar, H; Rymbekova, A; Cuadros-Espinoza, S; Huang, X; de Manuel, M; van der Valk, T; Lobon, I; Alvarez-Estape, M; Haber, M; Dolgova, O; Han, SJ; Este (2023). Ghost admixture in eastern gorillas. Nature Ecology & Evolution, 7(9), 1503-1514. DOI: 10.1038/s41559-023-02145-2https://doi.org/10.1038/s41559-023-02145-2
Metabolic rewiring induced by ranolazine improves melanoma responses to targeted therapy and immunotherapy2023-09-01Redondo-Munoz, M; Rodriguez-Baena, FJ; Aldaz, P; Caballe-Mestres, A; Moncho-Amor, V; Otaegi-Ugartemendia, M; Carrasco-Garcia, E; Olias-Arjona, A; Lash (2023). Metabolic rewiring induced by ranolazine improves melanoma responses to targeted therapy and immunotherapy. Nature Metabolism, 5(9), 1544-+. DOI: 10.1038/s42255-023-00861-4https://doi.org/10.1038/s42255-023-00861-4
Combined loss of CDH1 and downstream regulatory sequences drive early-onset diffuse gastric cancer and increase penetrance of hereditary diffuse gastric cancer2023-09-01Sao José, C; Garcia-Pelaez, J; Ferreira, M; Arrieta, O; André, A; Martins, N; Solís, S; Martínez-Benítez, B; Ordóñez-Sánchez, ML; Rodríguez-Torres, M; (2023). Combined loss of CDH1 and downstream regulatory sequences drive early-onset diffuse gastric cancer and increase penetrance of hereditary diffuse gastric cancer. Gastric Cancer, 26(5), 653-666. DOI: 10.1007/s10120-023-01395-0https://doi.org/10.1007/s10120-023-01395-0
260th ENMC International Workshop: Congenital myasthenic syndromes 11-13 March 2022, Hoofddorp, The Netherlands2023-09-01Spendiff, S; Dong, Y; Maggi, L; Cruz, PMR; Beeson, D; Lochmüller, H (2023). 260th ENMC International Workshop: Congenital myasthenic syndromes 11-13 March 2022, Hoofddorp, The Netherlands. Neuromuscular Disorders, 33(9), 111-118. DOI: 10.1016/j.nmd.2022.12.006https://doi.org/10.1016/j.nmd.2022.12.006
miR-29a Is Downregulated in Progenies Derived from Chronically Stressed Males2023-09-01Riesco, MF; Valcarce, DG; Sellés-Egea, A; Esteve-Codina, A; Herráez, MP; Robles, V (2023). miR-29a Is Downregulated in Progenies Derived from Chronically Stressed Males. International Journal Of Molecular Sciences, 24(18), 14107-. DOI: 10.3390/ijms241814107https://doi.org/10.3390/ijms241814107
Yolk sac cell atlas reveals multiorgan functions during human early development2023-08-18Goh, I; Botting, RA; Rose, A; Webb, S; Engelbert, J; Gitton, Y; Stephenson, E; Londono, MQ; Mather, M; Mende, N; Imaz-Rosshandler, I; Yang, L; Horsfal (2023). Yolk sac cell atlas reveals multiorgan functions during human early development. Science, 381(6659), eadd7564-+. DOI: 10.1126/science.add7564https://doi.org/10.1126/science.add7564
Copy Number Variation on ABCC2-DNMBP Loci Affects the Diversity and Composition of the Fecal Microbiota in Pigs2023-08-17Ramayo-Caldas, Y; Crespo-Piazuelo, D; Morata, J; González-Rodríguez, O; Sebastià, C; Castello, A; Dalmau, A; Ramos-Onsins, S; Alexiou, KG; Folch, JM; (2023). Copy Number Variation on ABCC2-DNMBP Loci Affects the Diversity and Composition of the Fecal Microbiota in Pigs. Microbiology Spectrum, 11(4), e0527122-. DOI: 10.1128/spectrum.05271-22https://doi.org/10.1128/spectrum.05271-22
A critical spotlight on the paradigms of FFPE-DNA sequencing2023-08-11Steiert, TA; Parra, G; Gut, M; Arnold, N; Trotta, JR; Tonda, R; Moussy, A; Gerber, Z; Abuja, PM; Zatloukal, K; Rocken, C; Folseraas, T; Grimsrud, MM; (2023). A critical spotlight on the paradigms of FFPE-DNA sequencing. Nucleic Acids Research, 51(14), 7143-7162. DOI: 10.1093/nar/gkad519https://doi.org/10.1093/nar/gkad519
Thymine DNA glycosylase regulates cell-cycle-driven p53 transcriptional control in pluripotent cells2023-08-03Aranda, S; Alcaine-Colet, A; Ballare, C; Blanco, E; Mocavini, I; Sparavier, A; Vizan, P; Borras, E; Sabido, E; Di Croce, L (2023). Thymine DNA glycosylase regulates cell-cycle-driven p53 transcriptional control in pluripotent cells. Molecular Cell, 83(15), 2673-+. DOI: 10.1016/j.molcel.2023.07.003https://doi.org/10.1016/j.molcel.2023.07.003
Inhibition of C5AR1 impairs osteoclast mobilization and prevents bone loss2023-08-02Pimenta-Lopes, C; Sanchez-de-Diego, C; Deber, A; Egea-Cortes, A; Valer, JA; Alcala, A; Mendez-Lucas, A; Esteve-Codina, A; Rosa, JL; Ventura, F (2023). Inhibition of C5AR1 impairs osteoclast mobilization and prevents bone loss. Molecular Therapy, 31(8), 2507-2523. DOI: 10.1016/j.ymthe.2023.04.022https://doi.org/10.1016/j.ymthe.2023.04.022
Single-cell atlases of two lophotrochozoan larvae highlight their complex evolutionary histories2023-08-01Piovani, L; Leite, DJ; Guerra, LAY; Simpson, F; Musser, JM; Salvador-Martinez, I; Marletaz, F; Jekely, G; Telford, MJ (2023). Single-cell atlases of two lophotrochozoan larvae highlight their complex evolutionary histories. Science Advances, 9(31), eadg6034-. DOI: 10.1126/sciadv.adg6034https://doi.org/10.1126/sciadv.adg6034
Integrated Multi-Omics Analysis for Inferring Molecular Players in Inclusion Body Myositis2023-08-01Canto-Santos, J; Valls-Roca, L; Tobias, E; Oliva, C; Garcia-Garcia, FJ; Guitart-Mampel, M; Andujar-Sanchez, F; Esteve-Codina, A; Martin-Mur, B; Padros (2023). Integrated Multi-Omics Analysis for Inferring Molecular Players in Inclusion Body Myositis. Antioxidants, 12(8), 1639-. DOI: 10.3390/antiox12081639https://doi.org/10.3390/antiox12081639
Novel covalent CDK7 inhibitor potently induces apoptosis in acute myeloid leukemia and synergizes with Venetoclax2023-07-29Gaur, T; Poddutoori, R; Khare, L; Bagal, B; Rashmi, S; Patkar, N; Tembhare, P; Pg, S; Shetty, D; Dutt, A; Zhang, Q; Konopleva, M; Platzbeckar, U; Gupt (2023). Novel covalent CDK7 inhibitor potently induces apoptosis in acute myeloid leukemia and synergizes with Venetoclax. Journal Of Experimental & Clinical Cancer Research, 42(1), 186-. DOI: 10.1186/s13046-023-02750-whttps://doi.org/10.1186/s13046-023-02750-w
Macrophage and neutrophil heterogeneity at single-cell spatial resolution in human inflammatory bowel disease2023-07-26Garrido-Trigo, A; Corraliza, AM; Veny, M; Dotti, I; Melon-Ardanaz, E; Rill, A; Crowell, HL; Corbi, A; Gudino, V; Esteller, M; alvarez-Teubel, I; Aguil (2023). Macrophage and neutrophil heterogeneity at single-cell spatial resolution in human inflammatory bowel disease. Nature Communications, 14(1), 4506-. DOI: 10.1038/s41467-023-40156-6https://doi.org/10.1038/s41467-023-40156-6
Eighty million years of rapid evolution of the primate Y chromosome2023-07-01Zhou, Y; Zhan, XY; Jin, JZ; Zhou, L; Bergman, J; Li, XM; Rousselle, MMC; Belles, MR; Zhao, L; Fang, MQ; Chen, JW; Fang, Q; Kuderna, L; Marques-Bonet, (2023). Eighty million years of rapid evolution of the primate Y chromosome. Nature Ecology & Evolution, 7(7), 1114-1130. DOI: 10.1038/s41559-022-01974-xhttps://doi.org/10.1038/s41559-022-01974-x
A Stenotrophomonas maltophilia TetR-Like Transcriptional Regulator Involved in Fatty Acid Metabolism Is Controlled by Quorum Sensing Signals2023-06-28Coves, X; Bravo, M; Huedo, P; Conchillo-Solé, O; Gómez, AC; Esteve-Codina, A; Dabad, M; Gut, M; Daura, X; Yero, D; Gibert, I (2023). A Stenotrophomonas maltophilia TetR-Like Transcriptional Regulator Involved in Fatty Acid Metabolism Is Controlled by Quorum Sensing Signals. Applied And Environmental Microbiology, 89(6), e0063523-. DOI: 10.1128/aem.00635-23https://doi.org/10.1128/aem.00635-23