TitleDateAuthorsDOI
Comparative Analysis of Single-Cell RNA Sequencing Methods2017-02-16Ziegenhain, C; Vieth, B; Parekh, S; Reinius, B; Guillaumet-Adkins, A; Smets, M; Leonhardt, H; Heyn, H; Hellmann, I; Enard, W (2017). Comparative Analysis of Single-Cell RNA Sequencing Methods. Molecular Cell, 65(4), 631-+. DOI: 10.1016/j.molcel.2017.01.023https://doi.org/10.1016/j.molcel.2017.01.023
Evidence that the rate of strong selective sweeps increases with population size in the great apes2017-02-14Nam, K; Munch, K; Mailund, T; Nater, A; Greminger, MP; Krützen, M; Marquès-Bonet, T; Schierup, MH (2017). Evidence that the rate of strong selective sweeps increases with population size in the great apes. Proceedings Of The National Academy Of Sciences Of The United States Of America, 114(7), 1613-1618. DOI: 10.1073/pnas.1605660114https://doi.org/10.1073/pnas.1605660114
Mutations in TRAPPC11 are associated with a congenital disorder of glycosylation.2017-02-01Matalonga, L; Bravo, M; Serra-Peinado, C; García-Pelegrí, E; Ugarteburu, O; Vidal, S; Llambrich, M; Quintana, E; Fuster-Jorge, P; Gonzalez-Bravo, MN; (2017). Mutations in TRAPPC11 are associated with a congenital disorder of glycosylation.. Human Mutation, 38(2), 148-151. DOI: 10.1002/humu.23145https://doi.org/10.1002/humu.23145
Genome-wide analysis of differential transcriptional and epigenetic variability across human immune cell types2017-01-26Ecker, S; Chen, L; Pancaldi, V; Bagger, FO; Fernández, JM; Pau, ECD; Juan, D; Mann, AL; Watt, S; Casale, FP; Sidiropoulos, N; Rapin, N; Merkel, A; Stu (2017). Genome-wide analysis of differential transcriptional and epigenetic variability across human immune cell types. Genome Biology, 18(1), 18-. DOI: 10.1186/s13059-017-1156-8https://doi.org/10.1186/s13059-017-1156-8
A Comparison of RNA-Seq Results from Paired Formalin-Fixed Paraffin-Embedded and Fresh-Frozen Glioblastoma Tissue Samples.2017-01-25Esteve-Codina, A; Arpi, O; Martinez-García, M; Pineda, E; Mallo, M; Gut, M; Carrato, C; Rovira, A; Lopez, R; Tortosa, A; Dabad, M; Del Barco, S; Heath (2017). A Comparison of RNA-Seq Results from Paired Formalin-Fixed Paraffin-Embedded and Fresh-Frozen Glioblastoma Tissue Samples.. Plos One, 12(1), e170632-. DOI: 10.1371/journal.pone.0170632https://doi.org/10.1371/journal.pone.0170632
Benchmarking of Whole Exome Sequencing and Ad Hoc Designed Panels for Genetic Testing of Hereditary Cancer.2017-01-04Feliubadaló, L; Tonda, R; Gausachs, M; Trotta, JR; Castellanos, E; López-Doriga, A; Teulé, A; Tornero, E; del Valle, J; Gel, B; Gut, M; Pineda, M; Gon (2017). Benchmarking of Whole Exome Sequencing and Ad Hoc Designed Panels for Genetic Testing of Hereditary Cancer.. Scientific Reports, 7(), 37984-. DOI: 10.1038/srep37984https://doi.org/10.1038/srep37984
ChimPipe: accurate detection of fusion genes and transcription-induced chimeras from RNA-seq data.2017-01-03Rodríguez-Martín, B; Palumbo, E; Marco-Sola, S; Griebel, T; Ribeca, P; Alonso, G; Rastrojo, A; Aguado, B; Guigó, R; Djebali, S (2017). ChimPipe: accurate detection of fusion genes and transcription-induced chimeras from RNA-seq data.. Bmc Genomics, 18(1), 7-. DOI: 10.1186/s12864-016-3404-9https://doi.org/10.1186/s12864-016-3404-9
Single-Cell Genomics Unravels Brain Cell-Type Complexity2017-01-01Guillaumet-Adkins, A; Heyn, H (2017). Single-Cell Genomics Unravels Brain Cell-Type Complexity. Advances In Experimental Medicine And Biology, 978(), 393-407. DOI: 10.1007/978-3-319-53889-1_20https://doi.org/10.1007/978-3-319-53889-1_20
Shared Oncogenic Pathways Implicated in Both Virus-Positive and UV-Induced Merkel Cell Carcinomas2017-01-01González-Vela, MDC; Curiel-Olmo, S; Derdak, S; Beltran, S; Santibañez, M; Martínez, N; Castillo-Trujillo, A; Gut, M; Sánchez-Pacheco, R; Almaraz, C; C (2017). Shared Oncogenic Pathways Implicated in Both Virus-Positive and UV-Induced Merkel Cell Carcinomas. Journal Of Investigative Dermatology, 137(1), 197-206. DOI: 10.1016/j.jid.2016.08.015https://doi.org/10.1016/j.jid.2016.08.015
A novel translational control mechanism involving RNA structures within coding sequences2017-01-01Jungfleisch, J; Nedialkova, DD; Dotu, I; Sloan, KE; Martinez-Bosch, N; Brüning, L; Raineri, E; Navarro, P; Bohnsack, MT; Leide, SA; Díez, J (2017). A novel translational control mechanism involving RNA structures within coding sequences. Genome Research, 27(1), 95-106. DOI: 10.1101/gr.209015.116https://doi.org/10.1101/gr.209015.116
Novel Candidate Genes and a Wide Spectrum of Structural and Point Mutations Responsible for Inherited Retinal Dystrophies Revealed by Exome Sequencing2016-12-22de Castro-Miró, M; Tonda, R; Escudero-Ferruz, P; Andrés, R; Mayor-Lorenzo, A; Castro, J; Ciccioli, M; Hidalgo, DA; Rodríguez-Ezcurra, JJ; Farrando, J; (2016). Novel Candidate Genes and a Wide Spectrum of Structural and Point Mutations Responsible for Inherited Retinal Dystrophies Revealed by Exome Sequencing. Plos One, 11(12), e0168966-. DOI: 10.1371/journal.pone.0168966https://doi.org/10.1371/journal.pone.0168966
Extreme genomic erosion after recurrent demographic bottlenecks in the highly endangered Iberian lynx2016-12-14Abascal, F; Corvelo, A; Cruz, F; Villanueva-Cañas, JL; Vlasova, A; Marcet-Houben, M; Martínez-Cruz, B; Cheng, JY; Prieto, P; Quesada, V; Quilez, J; Li (2016). Extreme genomic erosion after recurrent demographic bottlenecks in the highly endangered Iberian lynx. Genome Biology, 17(1), 251-. DOI: 10.1186/s13059-016-1090-1https://doi.org/10.1186/s13059-016-1090-1
From Wet-Lab to Variations: Concordance and Speed of Bioinformatics Pipelines for Whole Genome and Whole Exome Sequencing2016-12-01Laurie, S; Fernandez-Callejo, M; Marco-Sola, S; Trotta, JR; Camps, J; Chacón, A; Espinosa, A; Gut, M; Gut, I; Heath, S; Beltran, S (2016). From Wet-Lab to Variations: Concordance and Speed of Bioinformatics Pipelines for Whole Genome and Whole Exome Sequencing. Human Mutation, 37(12), 1263-1271. DOI: 10.1002/humu.23114https://doi.org/10.1002/humu.23114
Evolution and demography of the great apes2016-12-01Kuhlwilm, M; de Manuel, M; Nater, A; Greminger, MP; Krützen, M; Marques-Bonet, T (2016). Evolution and demography of the great apes. Current Opinion In Genetics & Development, 41(), 124-129. DOI: 10.1016/j.gde.2016.09.005https://doi.org/10.1016/j.gde.2016.09.005
Growth phase-dependent control of R27 conjugation is mediated by the interplay between the plasmid-encoded regulatory circuit TrhR/TrhY-HtdA and the cAMP regulon2016-12-01Gibert, M; Paytubi, S; Beltrán, S; Juárez, A; Balsalobre, C; Madrid, C (2016). Growth phase-dependent control of R27 conjugation is mediated by the interplay between the plasmid-encoded regulatory circuit TrhR/TrhY-HtdA and the cAMP regulon. Environmental Microbiology, 18(12), 5277-5287. DOI: 10.1111/1462-2920.13579https://doi.org/10.1111/1462-2920.13579
Whole exome sequencing analysis reveals TRPV3 as a risk factor for cardioembolic stroke2016-12-01Carrera, C; Jiménez-Conde, J; Derdak, S; Rabionet, K; Vives-Bauzá, C; Soriano-Tárrega, C; Giralt-Steinhauer, E; Mola-Caminal, M; Diaz-Navarro, RM; Tur (2016). Whole exome sequencing analysis reveals TRPV3 as a risk factor for cardioembolic stroke. Thrombosis And Haemostasis, 116(6), 1165-1171. DOI: 10.1160/TH16-02-0113https://doi.org/10.1160/TH16-02-0113
Increased DNA methylation variability in type 1 diabetes across three immune effector cell types2016-11-29Paul, DS; Teschendorff, AE; Dang, MAN; Lowe, R; Hawa, MI; Ecker, S; Beyan, H; Cunningham, S; Fouts, AR; Ramelius, A; Burden, F; Farrow, S; Rowlston, S (2016). Increased DNA methylation variability in type 1 diabetes across three immune effector cell types. Nature Communications, 7(), 13555-. DOI: 10.1038/ncomms13555https://doi.org/10.1038/ncomms13555
Integrative epigenome-wide analysis demonstrates that DNA methylation may mediate genetic risk in inflammatory bowel disease2016-11-25Ventham, NT; Kennedy, NA; Adams, AT; Kalla, R; Heath, S; O'Leary, KR; Drummond, H; Wilson, DC; Gut, IG; Nimmo, ER; Satsangi, J (2016). Integrative epigenome-wide analysis demonstrates that DNA methylation may mediate genetic risk in inflammatory bowel disease. Nature Communications, 7(), 13507-. DOI: 10.1038/ncomms13507https://doi.org/10.1038/ncomms13507
β-Glucan Reverses the Epigenetic State of LPS-Induced Immunological Tolerance2016-11-17Novakovic, B; Habibi, E; Wang, SY; Arts, RJW; Davar, R; Megchelenbrink, W; Kim, B; Kuznetsova, T; Kox, M; Zwaag, J; Matarese, F; van Heeringen, SJ; Ja (2016). β-Glucan Reverses the Epigenetic State of LPS-Induced Immunological Tolerance. Cell, 167(5), 1354-1368.e14. DOI: 10.1016/j.cell.2016.09.034https://doi.org/10.1016/j.cell.2016.09.034
Distinct Trends of DNA Methylation Patterning in the Innate and Adaptive Immune Systems2016-11-15Schuyler, RP; Merkel, A; Raineri, E; Altucci, L; Vellenga, E; Martens, JHA; Pourfarzad, F; Kuijpers, TW; Burden, F; Farrow, S; Downes, K; Ouwehand, WH (2016). Distinct Trends of DNA Methylation Patterning in the Innate and Adaptive Immune Systems. Cell Reports, 17(8), 2101-2111. DOI: 10.1016/j.celrep.2016.10.054https://doi.org/10.1016/j.celrep.2016.10.054