TitleDateAuthorsDOI
TRIM28 and Interacting KRAB-ZNFs Control Self-Renewal of Human Pluripotent Stem Cells through Epigenetic Repression of Pro-differentiation Genes2017-12-01Oleksiewicz, U; Gladych, M; Raman, AT; Heyn, H; Mereu, E; Chlebanowska, P; Andrzejewska, A; Sozanska, B; Samant, N; Fak, K; Auguscik, P; Kosinski, M; (2017). TRIM28 and Interacting KRAB-ZNFs Control Self-Renewal of Human Pluripotent Stem Cells through Epigenetic Repression of Pro-differentiation Genes. Stem Cell Reports, 9(6), 2065-2080. DOI: 10.1016/j.stemcr.2017.10.031https://doi.org/10.1016/j.stemcr.2017.10.031
Integrated transcriptional analysis unveils the dynamics of cellular differentiation in the developing mouse hippocampus2017-12-01Iacono G; Benevento M; Dubos A; Herault Y; van Bokhoven H; Nadif Kasri N; Stunnenberg HG (2017). Integrated transcriptional analysis unveils the dynamics of cellular differentiation in the developing mouse hippocampus. Scientific Reports, 7(1), 18073-18073. DOI: 10.1038/s41598-017-18287-whttps://doi.org/10.1038/s41598-017-18287-w
Single-cell absolute contact probability detection reveals chromosomes are organized by multiple low-frequency yet specific interactions.2017-11-24Cattoni, DI; Gizzi, AMC; Georgieva, M; Di Stefano, M; Valeri, A; Chamousset, D; Houbron, C; Déjardin, S; Fiche, JB; González, I; Chang, JM; Sexton, T; (2017). Single-cell absolute contact probability detection reveals chromosomes are organized by multiple low-frequency yet specific interactions.. Nature Communications, 8(1), 1753-. DOI: 10.1038/s41467-017-01962-xhttps://doi.org/10.1038/s41467-017-01962-x
Molecular and cellular reorganization of neural circuits in the human lineage2017-11-24Sousa, AMM; Zhu, Y; Raghanti, MA; Kitchen, RR; Onorati, M; Tebbenkamp, ATN; Stutz, B; Meyer, KA; Li, MF; Kawasawa, YI; Liu, FC; Perez, RG; Mele, M; Ca (2017). Molecular and cellular reorganization of neural circuits in the human lineage. Science, 358(6366), 1027-1032. DOI: 10.1126/science.aan3456https://doi.org/10.1126/science.aan3456
Morphometric, Behavioral, and Genomic Evidence for a New Orangutan Species2017-11-20Nater, A; Mattle-Greminger, MP; Nurcahyo, A; Nowak, MG; de Manuel, M; Desai, T; Groves, C; Pybus, M; Sonay, TB; Roos, C; Lameira, AR; Wich, SA; Askew, (2017). Morphometric, Behavioral, and Genomic Evidence for a New Orangutan Species. Current Biology, 27(22), 3487-+. DOI: 10.1016/j.cub.2017.09.047https://doi.org/10.1016/j.cub.2017.09.047
Histone H1 depletion triggers an interferon response in cancer cells via activation of heterochromatic repeats2017-11-16Izquierdo-Bouldstridge, A; Bustillos, A; Bonet-Costa, C; Aribau-Miralbés, P; García-Gomis, D; Dabad, M; Esteve-Codina, A; Pascual-Reguant, L; Peiró, S (2017). Histone H1 depletion triggers an interferon response in cancer cells via activation of heterochromatic repeats. Nucleic Acids Research, 45(20), 11622-11642. DOI: 10.1093/nar/gkx746https://doi.org/10.1093/nar/gkx746
Tumor-associated macrophages (TAMs) depend on ZEB1 for their cancer-promoting roles2017-11-15Cortés, M; Sanchez-Moral, L; de Barrios, O; Fernández-Aceñero, MJ; Martínez-Campanario, MC; Esteve-Codina, A; Darling, DS; Gyorffy, B; Lawrence, T; De (2017). Tumor-associated macrophages (TAMs) depend on ZEB1 for their cancer-promoting roles. Embo Journal, 36(22), 3336-3355. DOI: 10.15252/embj.201797345https://doi.org/10.15252/embj.201797345
Innate Cell-Mediated Cytotoxic Activity of European Sea Bass Leucocytes Against Nodavirus-Infected Cells: A Functional and RNA-seq Study2017-11-13Chaves-Pozo, E; Valero, Y; Esteve-Codina, A; Gómez-Garrido, J; Dabad, M; Alioto, T; Meseguer, J; Esteban, MA; Cuesta, A (2017). Innate Cell-Mediated Cytotoxic Activity of European Sea Bass Leucocytes Against Nodavirus-Infected Cells: A Functional and RNA-seq Study. Scientific Reports, 7(1), 15396-. DOI: 10.1038/s41598-017-15629-6https://doi.org/10.1038/s41598-017-15629-6
A 3-way hybrid approach to generate a new high-quality chimpanzee reference genome (Pan tro 3.0)2017-10-30Kuderna, LFK; Tomlinson, C; Hillier, LW; Tran, A; Fiddes, IT; Armstrong, J; Laayouni, H; Gordon, D; Huddleston, J; Perez, RG; Povolotskaya, I; Armero, (2017). A 3-way hybrid approach to generate a new high-quality chimpanzee reference genome (Pan tro 3.0). Gigascience, 6(11), 1-6. DOI: 10.1093/gigascience/gix098https://doi.org/10.1093/gigascience/gix098
Biallelic mutation of UNC50, encoding a protein involved in AChR trafficking, is responsible for arthrogryposis2017-10-15Abiusi, E; D'Alessandro, M; Dieterich, K; Quevarec, L; Turczynski, S; Valfort, AC; Mezin, P; Jouk, PS; Gut, M; Gut, I; Bessereau, JL; Melki, J (2017). Biallelic mutation of UNC50, encoding a protein involved in AChR trafficking, is responsible for arthrogryposis. Human Molecular Genetics, 26(20), 3989-3994. DOI: 10.1093/hmg/ddx288https://doi.org/10.1093/hmg/ddx288
A DNA methylation map of human cancer at single base-pair resolution.2017-10-05Vidal, E; Sayols, S; Moran, S; Guillaumet-Adkins, A; Schroeder, MP; Royo, R; Orozco, M; Gut, M; Gut, I; Lopez-Bigas, N; Heyn, H; Esteller, M (2017). A DNA methylation map of human cancer at single base-pair resolution.. Oncogene, 36(40), 5648-5657. DOI: 10.1038/onc.2017.176https://doi.org/10.1038/onc.2017.176
MHC class I diversity in chimpanzees and bonobos2017-10-01Maibach, V; Hans, JB; Hvilsom, C; Marques-Bonet, T; Vigilant, L (2017). MHC class I diversity in chimpanzees and bonobos. Immunogenetics, 69(10), 661-676. DOI: 10.1007/s00251-017-0990-xhttps://doi.org/10.1007/s00251-017-0990-x
Dual MET and ERBB inhibition overcomes intratumor plasticity in osimertinib-resistant-advanced non-small-cell lung cancer (NSCLC)2017-10-01Martinez-Marti, A; Felip, E; Matito, J; Mereu, E; Navarro, A; Cedrés, S; Pardo, N; de Castro, AM; Remon, J; Miquel, JM; Guillaumet-Adkins, A; Nadal, E (2017). Dual MET and ERBB inhibition overcomes intratumor plasticity in osimertinib-resistant-advanced non-small-cell lung cancer (NSCLC). Annals Of Oncology, 28(10), 2451-2457. DOI: 10.1093/annonc/mdx396https://doi.org/10.1093/annonc/mdx396
The utility of Next Generation Sequencing for molecular diagnostics in Rett syndrome2017-09-25Vidal, S; Brandi, N; Pacheco, P; Gerotina, E; Blasco, L; Trotta, JR; Derdak, S; O'Callaghan, MD; Garcia-Cazorla, A; Pineda, M; Armstrong, J (2017). The utility of Next Generation Sequencing for molecular diagnostics in Rett syndrome. Scientific Reports, 7(1), 12288-. DOI: 10.1038/s41598-017-11620-3https://doi.org/10.1038/s41598-017-11620-3
Evaluation of single-cell genomics to address evolutionary questions using three SAGs of the choanoflagellate Monosiga brevicollis2017-09-08López-Escardó, D; Grau-Bové, X; Guillaumet-Adkins, A; Gut, M; Sieracki, ME; Ruiz-Trillo, I (2017). Evaluation of single-cell genomics to address evolutionary questions using three SAGs of the choanoflagellate Monosiga brevicollis. Scientific Reports, 7(1), 11025-. DOI: 10.1038/s41598-017-11466-9https://doi.org/10.1038/s41598-017-11466-9
Copy number rather than epigenetic alterations are the major dictator of imprinted methylation in tumors.2017-09-07Martin-Trujillo, A; Vidal, E; Monteagudo-Sánchez, A; Sanchez-Delgado, M; Moran, S; Mora, JRH; Heyn, H; Guitart, M; Esteller, M; Monk, D (2017). Copy number rather than epigenetic alterations are the major dictator of imprinted methylation in tumors.. Nature Communications, 8(1), 467-. DOI: 10.1038/s41467-017-00639-9https://doi.org/10.1038/s41467-017-00639-9
Whole exome sequencing as a diagnostic tool for patients with ciliopathy-like phenotypes2017-08-11Castro-Sánchez, S; Alvarez-Satta, M; Tohamy, MA; Beltran, S; Derdak, S; Valverde, D (2017). Whole exome sequencing as a diagnostic tool for patients with ciliopathy-like phenotypes. Plos One, 12(8), e0183081-. DOI: 10.1371/journal.pone.0183081https://doi.org/10.1371/journal.pone.0183081
Transcriptional mechanisms underlying life-history responses to climate change in the three-spined stickleback2017-08-01Kim, SY; Costa, MM; Esteve-Codina, A; Velando, A (2017). Transcriptional mechanisms underlying life-history responses to climate change in the three-spined stickleback. Evolutionary Applications, 10(7), 718-730. DOI: 10.1111/eva.12487https://doi.org/10.1111/eva.12487
Adaptive Mistranslation Accelerates the Evolution of Fluconazole Resistance and Induces Major Genomic and Gene Expression Alterations in Candida albicans2017-08-01Weil, T; Santamaria, R; Lee, W; Rung, J; Tocci, N; Abbey, D; Bezerra, AR; Carreto, L; Moura, GR; Bayés, M; Gut, IG; Csikasz-Nagy, A; Cavalieri, D; Ber (2017). Adaptive Mistranslation Accelerates the Evolution of Fluconazole Resistance and Induces Major Genomic and Gene Expression Alterations in Candida albicans. Msphere, 2(4), e00167-17-. DOI: 10.1128/mSphere.00167-17https://doi.org/10.1128/mSphere.00167-17
Novel efficient genome-wide SNP panels for the conservation of the highly endangered Iberian lynx2017-07-21Kleinman-Ruiz, D; Martínez-Cruz, B; Soriano, L; Lucena-Perez, M; Cruz, F; Villanueva, B; Fernández, J; Godoy, JA (2017). Novel efficient genome-wide SNP panels for the conservation of the highly endangered Iberian lynx. Bmc Genomics, 18(1), 556-. DOI: 10.1186/s12864-017-3946-5https://doi.org/10.1186/s12864-017-3946-5