The three-dimensional folding of chromatin plays roles in almost all aspect of genome regulation, including gene expression, chromosome segregation and genome stability. Although the structure of chromatin at the level of several nucleosomes has been described in some detail, many aspects of higher...

The READNA consortium includes projects to accelerate new breakthrough DNA sequencing technologies and methods to enhance existing analysis methods. The consortium joins 18 European partners from both academia and industry, and launches with a €12m grant via the European Commission's seventh...

On 1 February 2011, a consortium of leading European research institutes begun developing a European infrastructure for genome sequencing and genotyping. Led by the Max-Planck-Institute for Molecular Genetics in Germany and funded by the European Commission, the European Sequencing and Genotyping...

SYBARIS is a systems biology study of the specificity of response of the cell-mediated immune system to fungal microorganisms in order to determine the genetic basis of susceptibility to fungal disease and elucidate molecular mechanisms of drug resistance in fungal pathogens. An integrative...

In 2007 the EvA project was given a €3 million European Union grant to fund its groundbreaking research in COPD. The project brings together clinical medicine, radiology and image analysis and genetics including gene expression analysis, laboratory diagnostics and bioinformatics. The project...

One third of the world's overall population is infected with Mycobacterium tuberculosis (Mtb), the causing agent of Tuberculosis (TB). About 95% of those, are thought to be in latent infection where Mtb rarely replicates. Nevertheless, ~10% of latent infections eventually progresses to active...