Charting SARS-CoV-2 entry factors in human tissues

The project aims to perform a comprehensive analysis of how tissues including the nasal mucosa, lung, gut and kidney are susceptible to infection. Holger Heyn, leader of the Single Cell Genomics team at the CNAG-CRG, will carry out single-cell resolved characterization of different cell populations to pinpoint molecules that are crucial for viral entry into cells, as well as identify potential target molecules to block this process on subsequent experimental validation.

The project is led by Meritxell Genescà at the Vall d’Hebron Research Institute and Joaquín Burgos at the Vall d’Hebron Hospital and funded by La Marató de TV3 and Catalunya Radio.

Meritxell Genescà (VHIR), Joaquín Burgos (Vall d’Hebron Hospital)