The Genomic Data Infrastructure (GDI) project is enabling access to genomic and related phenotypic and clinical data across Europe. It is doing this by establishing a federated, sustainable and secure infrastructure to access the data. It builds on the outputs of the Beyond 1 Million Genomes (B1MG) project and is realising the ambition of the 1+Million Genomes (1+MG) initiative.

The data: The project involves human genomic and related phenotypic and clinical data held in databases across Europe. The project will focus on the Genome of Europe (a network of national reference genome collections), and cancer and infectious disease use cases. “Real” synthetic data will be used for validation before data are available through the infrastructure.

Who will access it?: Controlled access will be given to approved clinicians, scientists in the public and private sector and healthcare policy makers. Non-sensitive and aggregated data will be openly discoverable through the European Genome Dashboard and a federated query system. This system will support genotypic and phenotypic queries in natural language.

What are the benefits?: Insights from the data will support improved clinical diagnostics, treatments and predictive medicine for European citizens. The project will also lead to better public health measures to benefit citizens, healthcare systems and the economy.

Who is running it?: The GDI project brings together experts in life science, medicine, computer science, ethics and law from 54 project partners across 20 countries and two infrastructure organisations. They will ensure access to datasets is secure, ethical and compliant with European and national law.

Project website:

Serena Scollen (ELIXIR Human Genomics and Translational Data team)