Deadline: 
Apr 30, 2026
Description: 

The Position

We are seeking candidates for a collaborative PhD thesis project in bioinformatics that will address how inflammaging targets stem cells. We aim at modifying specific inflammatory pathways to improve fitness of aged stem cells. This project will be jointly directed by Dr Anna Esteve-Codina (CNAG, UB) and the group of Cristina López-Rodríguez and Jose Aramburu (UPF).

The Immunology group at UPF is developing different projects, from hematopoietic stem cell function to anti-tumor immunotherapy and immunometabolism. Recent Publications: Zadra et al. 2025 Cancer Letters; Riera-Borrull et al 2024 BioRxiv; Traveset et al 2024 Blood Advances; Lunazzi et al 2021 Journal of Immunology; Huerga Encabo et al 2020 Journal of Experimental Medicine; Aramburu and Lopez-Rodriguez 2019 Frontiers in Immunology; Buxadé et al 2018 Journal of Experimental Medicine; Tellechea et al 2018 Journal of Immunology.
 
The Functional Genomics Team at CNAG has broad experience in analyzing multiomic datasets involving scRNA-seq, scATAC-seq, sc-multiome, bulk RNA-seq, EM-seq and long-read sequencing technologies from healthy human tissues, cancer and other diseases. Recent Publications: Montserrat-Ayuso et al 2024 BMC Bioinformatics, Reineri et al 2024 BioRxiv, Montserrat-Ayuso et al 2025 BioRxiv, Esteve-Codina et al 2021 Scientific Reports, Esteve-Codina et al 2021 Clinical Cancer Research, Esteve-Codina et al 2020 Allergy, Esteve-Codina et al 2019 Genome Research.
 
 
Job objective
 
 
The selected candidate will enroll in the International PhD Program in Biomedical Research at UPF, gaining experience in bioinformatics and computational biology applied to aging and inflammatory responses. Usual methodologies will mainly consist of single cell bioinformatics analysis, and also advanced gene expression analysis (scRNA-seq, RNA-seq, ATAC-seq), spectral flow cytometry, and the use of in vivo mouse models for human aging. 
 
 
Requirements
 
Degree: The candidate must have a MSc in Bioinformatics, and preferably, a BSc in Bioinformatics. A BSc in Biology, Biomedicine, Biochemistry, Biotechnology or equivalent, will be considered. 
 
Languages: Fluency in written and spoken English is required.
 
Academic score: Ideally must be in the top 20% of their graduating class (approximately a score of 8.4 on a 1-10 scale) to ensure good chances in competitive predoctoral calls.
 
We value previous experience in bioinformatics and immunology projects.
 
 
Applications
 
Email to Anna Esteve-Codina (anna.esteve@cnag.eu), Cristina López-Rodríguez (cristina.lopez-rodriguez@upf.edu) or Jose Aramburu (jose.aramburu@upf.edu) with subject Ref: PhD in Bioinformatics UPF/CNAG/UB.
 
Please include your CV, full academic MSc and BSc transcripts, and provide one or two contacts (principal investigator level, with phone number and email) for references.