Deadline: 
Jul 31, 2025
Description: 

 

CNAG – The Institute

 

The CNAG Consortium carries out large-scale projects in DNA/RNA analysis for the improvement of quality of life in collaboration with the Spanish, European and International Research Community. The Centro Nacional de Análisis Genómico (CNAG) is one of the largest Genome Sequencing Centers in Europe, with several Illumina and Oxford Nanopore Technologies sequencers, state-of-the-art single-cell equipment, and an extensive informatics infrastructure. The operation is certified ISO 9001 and accredited ISO 17025, delivering standardized, high-quality data for research and clinics. The CNAG has over 125, structured in different units such Bioinformatics, Sequencing, Single-cell, Research and Corporate Management, and participates in major International Genome Initiatives and EU-funded projects.

 

 

The Role

 

We are hiring 2 Computational Biology PhD students to lead projects in immuno-oncology (IO) and immune-mediated inflammatory diseases (IMID), respectively. 

 

In IO, we aim to delineate mechanisms and dynamics of immune cell infiltration and plasticity in tumors, to provide precise prediction of therapy success. 

In IMID, we seek to identify inflammatory disease-specific biomarkers to understand mechanisms driving disease progression and response to treatment across large acute and chronic patient cohorts. 

 

While applying single-cell and spatial genomics tools to delineate the complexity of tumors or inflamed tissues, a particular focus lies on the use of blood samples as a liquid biopsy tool for repeated, longitudinal studies. This will allow us to build predictive models for patient outcome and, eventually, foundation models for immune cell plasticity and natural/clinical perturbations. 

 

We are looking for 2 enthusiastic computational scientists, motivated to improve patient outcome and healthcare. Together, we aim to bring single-cell and spatial genomics applications into clinical use and to advance pathology assessment with high-dimensional genomics readouts (next-generation pathology). 

 

The candidates will be integrated in the Single Cell Genomics Team, a highly collaborative, international work environment with well-experienced colleagues in single-cell and spatial data generation and analysis. They will be involved in projects that aim to understand the molecular and cellular basis of immune cell action, through the application of multi-omics single-cell and spatial technologies on clinical samples. 

 

Candidates’ tasks include the analysis of single-cell and spatial data and the development of statistical methods for the integration with clinical patient information. We are looking for highly motivated and a creative thinking individuals, who are interested in working in an environment where the technical sophistication of single-cell and spatial technologies meets innovative approaches for interpreting data and generating new knowledge. We require the ability for working in a multi-disciplinary team on collaborative projects.

 

 

Whom would we like to hire? 

 

·       You have completed a Master in Bioinformatics, Mathematics, Statistics or similar. 

·       You are competent in Python or R.

·       You have excellent knowledge of Computational Biology.

·       Experience in single-cell and/or spatial analysis

 

The Offer 

  • Contract duration: 3 Years

  • Estimated annual gross salary: Salary is commensurate with qualifications and consistent with our pay scales.

  • Target start date: September 2025

            

We provide a highly stimulating environment with state-of-the-art infrastructures, and unique professional career development opportunities. 

 

We offer and promote a diverse and inclusive environment and welcomes applicants regardless of age, disability, gender, nationality, race, religion or sexual orientation.

 

We are committed to reconcile work and family life for our employees and are offering the opportunity to benefit from annual leave and flexible working hours.

 

 

Application Procedure

All applications must include:

  • A motivation letter addressed to Dr Holger Heyn.

  • A complete CV including contact details.

  • Contact details of two referees.

 

All applications must be addressed to: Dr. Holger Heyn - holger.heyn@cnag.eu / CC: mireya.fernandez@cnag.eu

 

Deadline: Please submit your application by 31/07/2025

 

Interview: Shortlisted candidates will be called for an interview

 

 

Please, see all of our job opportunities in the Career site of CNAG website: https://www.cnag.eu/jobs