CNAG – The Institute

The CNAG Consortium carries out large-scale projects in DNA/RNA analysis for the improvement of quality of life in collaboration with the Spanish, European and International Research Community. The Centro Nacional de Análisis Genómico (CNAG) is one of the largest Genome Sequencing Centers in Europe, with several Illumina and Oxford Nanopore Technologies sequencers, state-of-the-art single-cell equipment, and an extensive informatics infrastructure. The operation is certified ISO 9001 and accredited ISO 17025, delivering standardized, high-quality data for research and clinics. The CNAG has over 125 professionals and participates in major International Genome Initiatives and EU-funded projects.

The CNAG has more than 100 professionals, structured in different units such Bioinformatics, Sequencing, Single-cell, Research and Corporate Management. 

The Role

We have an opening for a Nextflow genomics pipelines developer in the Variant Calling and Analysis team. The team collaborates with external and internal researchers on their sequencing analysis projects and works closely with CNAG’s Sequencing Unit and the Production Bioinformatics team. The team develops and operates state-of-the-art pipelines and tools to ISO accredited standards. The team focus is in the identification and annotation of germline variants and somatic mutations from short read and long read sequencing data, mostly from human data but also from many other organisms. In addition, the team collaborates in tertiary analysis in many projects.

The successful candidate will join the Variant Calling and Analysis team, coordinated by Dr. Raul Tonda (https://www.cnag.eu/teams/bioinformatics-unit/variant-calling-and-analysis). The team is part of the CNAG Bioinformatics Unit (led by Dr. Sergi Beltran), which has over 30 members and offers continuous growth and support on a professional level. 

The team works in a stimulating scientific environment, applying state-of-the-art technologies to breakthrough research projects in Genomics that have an impact on people’s health. The team is involved in the IMPaCT – Datos 2 project, funded by Instituto de Salud Carlos III.

   Responsibilities include:

1. Develop and implement bioinformatics pipelines for genomics data analysis using Nextflow.
2. Contribute to pipeline benchmarking.
3. Design and implement automated validation tests.
4. Contribute to the integration of the pipelines as part of larger initiatives
5. Participate in collaborative task forces and networks

Whom would we like to hire? 

•            MSc in Bioinformatics or related discipline.

•           A minimum experience of 1 year developing pipelines with Nextflow and NF-Core.

•           A minimum experience of 1 year in the analysis of Next Generation Sequencing whole exome or genome data.

•           Knowledge of version control software

•           Knowledge of software containers

•           Experience with Unix operating systems, including shell scripts.

•           Working experience in languages such as Python, R or Perl

•           Excellent organisational, prioritising, communication and interpersonal skills.

•           Strong problem-solving and critical thinking abilities

•           Good spoken and written English.

Nice to have:

•           Familiarity with High-Performance Computing (HPC) systems and parallel computing 

•           Experience within diagnostic settings and the analysis and interpretation of genomic data linked to personal clinical information.

•           Experience in disease genomics. 

The Offer 

•           Contract duration: Open-ended linked to a project

•           Estimated annual gross salary: Salary is commensurate with qualifications and consistent with our pay scales.

•           Target start date: as soon as possible

We provide a highly stimulating environment with state-of-the-art infrastructures, and unique professional career development opportunities. 

We offer and promote a diverse and inclusive environment and welcomes applicants regardless of age, disability, gender, nationality, race, religion or sexual orientation.

We are committed to reconcile work and family life for our employees and are offering the opportunity to benefit from annual leave and flexible working hours.

Application Procedure

All applications must include:

•            A complete CV including contact details.

•           Contact details of two referees.

All applications must be addressed to:

Mireya Fernández – mireya.fernandez@cnag.eu

Raul Tonda – raul.tonda@cang.eu

Deadline: Please submit your application by 15/06/2025

Interview: Shortlisted candidates will be called for an interview

Please, see all of our job opportunities in the Career site of CNAG website: https://www.cnag.eu/jobs